| Tamsin Greig | as | Dr. Caroline Todd | |
| Julian Rhind-Tutt | as | Dr. Mac McCartney | |
| Stephen Mangan | as | Dr. Guy Secretan | |
| Pippa Haywood | as | Joanna Clore | |
| Mark Heap | as | Dr. Alan Statham | |
| Michelle Gomez | as | Sue White | |
| Karl Theobald | as | Dr. Martin Dear | |
| Sarah Alexander | as | Dr. Angela Hunter | |
| Olivia Colman | as | Harriet Schulenburg | |
| Oliver Chris | as | Boyce | |
| Sally Bretton | as | Kim Alabaster | |
| Lucinda Raikes | as | Karen Ball | |
| Paterson Joseph | as | Lyndon | |
| Sally Phillips | as | Holly Hawkes (Series 2) | |
| Darren Boyd | as | Jake (Series 2) |
Series: 2
Episodes: 18
Transmitted: 2004-2007
Channel 4
TalkBack Productions